Sometimes Simconnect simply stops during a long flight, causing the program to be unresponsive, because it's not receiving any data from the sim. Usually a restart fixes it.
Note that, for the auto-restarter to work, it requires the program would QUIT/CRASH, since there's no way for the auto-restarter to detect it's just "waiting" data from the sim that doesn't arrive because Simconnect is stuck. And, the auto-restarter is not immediate: it waits for 1 minute *after* the couatl.exe quits or crashed before restarting it. And if you select "Exit" from the tray-bar icon menu, it won't auto-restart anymore for that sim session.